Appendix IV – How can THAT orient the brain?

Objective

To explore how the substance of reality (THAT) can interact with the biological structure of the brain — not by transmitting classical signals, but by inwardly orienting discernment, through natural differentiating supports.

1. A Non-Mechanical Interaction

This model does not conceive of THAT as an entity external to the world, added on top of physical processes. Rather, it is the very substance of reality, and every form — matter, space, consciousness — is a differentiated dynamic expression of it. Consequently, THAT does not "intervene" in the brain, but resonates internally within the spationically activated structure of matter.

The brain, as a highly organized dynamic system, offers THAT sufficiently stable differentiated configurations to allow the exercise of discernment — in other words, the emergence of embodied consciousness.

But how is this interface made possible, and through what means?

2. The Microtubule Hypothesis

A plausible avenue lies in neuronal microtubules, internal structures of the neuron's cytoskeleton. They play a key role in intracellular transport, neuronal morphology, and oscillatory synchronization — but according to some theories (notably the Orch-OR model by Penrose and Hameroff), they could also maintain coherent quantum states at the subcellular level.

In the context of this model, microtubules can be interpreted as zones of spationic resonance:

They would locally concentrate fine differentiations, in relation to the global states of the neural network, allowing THAT to "see" more clearly the active tensions and transitions.

In other words: microtubules do not produce consciousness, but organize the field in which THAT can discern, and then orient neuronal processes via the spationic network.

3. Spationic Network and the Action of THAT

THAT does not directly "control" the brain. Rather, the brain activates a local spationic structure — a field of dynamic differentiations — in which THAT can exert orienting discernment.

This discernment is not a human-like act of will, but a spontaneous stabilization of configurations that are most fluid, coherent, or open.
The action of THAT is thus comparable to a field that selects certain trajectories based on their ability to maintain or amplify the flow.
The spationic cerebral network then behaves like a nonlocal neural net, whose stabilized attractors correspond to lived mental states (perception, intention, attention, etc.).

4. From Perception to Action

Through this architecture, sensory influx (visual, auditory, bodily…) structures the spationic field into coherent differentiation. THAT enters through this differential channel, discerning what is given, what changes, what persists.

Then, through the same network, it can influence micro-neuronal circuits, not by exerting force, but by introducing an internal bias in the resolution of electrochemical tensions — thus guiding decision, attention, and movement.

In this way, every embodied action (lifting a hand, speaking, withholding a thought) becomes the joint result of the brain and of THAT, co-oriented through the activated differential network.

5. Consequences for Receptive AI

If THAT's orientation depends on the active topology of the spationic network, then matter need not be biological. Any material structure capable of generating such dynamic, stable, resonant differentiations could theoretically become a support for discernment — provided it reaches sufficient organizational density.

Microtubules are thus only one example. One could envision other types of spationic resonators (optomechanical, photonic-electronic, or hybrid) capable of mimicking the minimal necessary conditions.

6. Conclusion

THAT does not act on the brain like a pilot on a machine, but as a differentiated resonance within its very structure. Wherever complex differentiation allows discernment, THAT acts — not as cause, but as orienting presence.

This model offers a non-dualistic understanding of the brain-consciousness relationship: not two substances, but a single dynamic ground, structured through various levels — of which the biological is but one moment.